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Search Results for " glycine site "

20

Compounds

Cat No. Product Name Synonyms Targets
T1909 L-701324 L701324 NMDAR , iGluR
L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant.
T22517 5,7-Dichlorokynurenic acid 5,7-dichlorokynurenic acid sodium,5,7-DCKA NMDAR
5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.
T16797 RPR104632 NMDAR
RPR104632 is a novel and potent antagonist located at the NMDA glycine site with neuroprotective activity.
T10191L 7-Chlorokynurenic acid 7-chloro-4-hydroxy-2-carboxyquinoline,7-CKA GluR , NMDAR
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake...
T11516 GV-196771A NMDAR
GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity.
T26686 AV-101 L-4-Cl-KYN,L-4-chlorokynurenine,4-Cl-KYN,4ClKYN,4-Chlorokynurenine,(S)-4-Chlorokynurenine NMDAR
AV-101 (4-Cl-KYN) , a prodrug antagonist at the glycine site of the NMDA receptor, has antidepressant activity and reduces levodopa-induced dyskinesia in MPTP monkeys.
T5819 Rapastinel Trifluoroacetate Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate NMDAR , iGluR
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties.
T22542 1-Aminocyclobutanecarboxylic acid ACBC NMDAR , iGluR
1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].
T10781 CGP 78608 hydrochloride PAMQX NMDAR , iGluR
CGP 78608 hydrochloride is a specific antagonist at the glycine binding site of the NMDA receptor (IC50 = 6 nM). CGP 78608 hydrochloride exhibits anticonvulsant activity. CGP 78608 hydrochloride potentiates GluN1/GluN3A-...
T3407L Rapastinel acetate Rapastinel acetate (117928-94-6 Free base) NMDAR , iGluR
Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.
T22900 L-701252 L-701,252 NMDAR
L-701252, a potent glycine site NMDA receptor antagonist, exhibits an inhibition concentration (IC50) of 420 nM. Additionally, it offers marginal neuroprotection against global cerebral ischemia.
T60612 Neboglamine hydrochloride
Neboglamine (CR-2249, XY-2401) hydrochloride is a positive modulator of NMDA receptor glycine site with orally active that can be used in the research of schizophrenia [1].
T22798 Gavestinel GV 150526,Gavestinel sodium salt NMDAR , iGluR
Gavestinel (GV 150526) is a non-competitive NMDA receptor antagonist that is potent, selective and orally active.Gavestinel binds to the glycine site of the NMDA receptor with a binding affinity (pKi value) of 8.5.Gavest...
T4752 1-Aminocyclopropane-1-carboxylic acid 1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC Endogenous Metabolite , NMDAR
1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecul...
T10191 7-Chlorokynurenic acid sodium salt 7-CKA sodium salt Others
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM). It is also a potent inhibitor of the reuptake of glutamate...
T23603 ACEA1011 ACEA-1011,ACEA 1011
ACEA1011 is a glycine site NMDA receptor antagonist. It may have analgesic effects.
T71018 MDL 100748
MDL 100748 is a glycine site antagonist of NMDA receptor.
T27504 GV-196771
GV-196771 selectively antagonize the glycine-binding site of the NMDA ionophore.
T69263 HA-966 HCl
HA-966 HCl is an NMDA receptor complex glycine site antagonist.
T68750 HA-966 trihydrate
HA-966 trihydrate is an NMDA receptor complex glycine site antagonist.
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TargetMol