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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1909 | L-701324 | L701324 | NMDAR , iGluR |
L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant. | |||
T22517 | 5,7-Dichlorokynurenic acid | 5,7-dichlorokynurenic acid sodium,5,7-DCKA | NMDAR |
5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist. | |||
T16797 | RPR104632 | NMDAR | |
RPR104632 is a novel and potent antagonist located at the NMDA glycine site with neuroprotective activity. | |||
T10191L | 7-Chlorokynurenic acid | 7-chloro-4-hydroxy-2-carboxyquinoline,7-CKA | GluR , NMDAR |
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake... | |||
T11516 | GV-196771A | NMDAR | |
GV-196771A A novel NMDA receptor glycine site antagonist with potent antinociceptive activity. | |||
T26686 | AV-101 | L-4-Cl-KYN,L-4-chlorokynurenine,4-Cl-KYN,4ClKYN,4-Chlorokynurenine,(S)-4-Chlorokynurenine | NMDAR |
AV-101 (4-Cl-KYN) , a prodrug antagonist at the glycine site of the NMDA receptor, has antidepressant activity and reduces levodopa-induced dyskinesia in MPTP monkeys. | |||
T5819 | Rapastinel Trifluoroacetate | Thr-Pro-Pro-Thr-NH2 Trifluoroacetate,GLYX-13 Trifluoroacetate | NMDAR , iGluR |
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. | |||
T22542 | 1-Aminocyclobutanecarboxylic acid | ACBC | NMDAR , iGluR |
1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1]. | |||
T10781 | CGP 78608 hydrochloride | PAMQX | NMDAR , iGluR |
CGP 78608 hydrochloride is a specific antagonist at the glycine binding site of the NMDA receptor (IC50 = 6 nM). CGP 78608 hydrochloride exhibits anticonvulsant activity. CGP 78608 hydrochloride potentiates GluN1/GluN3A-... | |||
T3407L | Rapastinel acetate | Rapastinel acetate (117928-94-6 Free base) | NMDAR , iGluR |
Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects. | |||
T22900 | L-701252 | L-701,252 | NMDAR |
L-701252, a potent glycine site NMDA receptor antagonist, exhibits an inhibition concentration (IC50) of 420 nM. Additionally, it offers marginal neuroprotection against global cerebral ischemia. | |||
T60612 | Neboglamine hydrochloride | ||
Neboglamine (CR-2249, XY-2401) hydrochloride is a positive modulator of NMDA receptor glycine site with orally active that can be used in the research of schizophrenia [1]. | |||
T22798 | Gavestinel | GV 150526,Gavestinel sodium salt | NMDAR , iGluR |
Gavestinel (GV 150526) is a non-competitive NMDA receptor antagonist that is potent, selective and orally active.Gavestinel binds to the glycine site of the NMDA receptor with a binding affinity (pKi value) of 8.5.Gavest... | |||
T4752 | 1-Aminocyclopropane-1-carboxylic acid | 1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC | Endogenous Metabolite , NMDAR |
1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecul... | |||
T10191 | 7-Chlorokynurenic acid sodium salt | 7-CKA sodium salt | Others |
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM). It is also a potent inhibitor of the reuptake of glutamate... | |||
T23603 | ACEA1011 | ACEA-1011,ACEA 1011 | |
ACEA1011 is a glycine site NMDA receptor antagonist. It may have analgesic effects. | |||
T71018 | MDL 100748 | ||
MDL 100748 is a glycine site antagonist of NMDA receptor. | |||
T27504 | GV-196771 | ||
GV-196771 selectively antagonize the glycine-binding site of the NMDA ionophore. | |||
T69263 | HA-966 HCl | ||
HA-966 HCl is an NMDA receptor complex glycine site antagonist. | |||
T68750 | HA-966 trihydrate | ||
HA-966 trihydrate is an NMDA receptor complex glycine site antagonist. |